This is the second edition of the successful textbook written by the prize-winning scientist Andreas Ziegler, former President of the German Region of the International Biometric Society, and Inke R. Konig, who has been teaching the subject over many years. The book gives a comprehensive introduction into the relevant statistical methods in genetic epidemiology. The second edition is thoroughly revised, partly rewritten and includes new chapters on traditional family studies and state-of-the-art genome-wide association studies. The book is ideally suited for advanced students in epidemiology, genetics, statistics, bioinformatics and biomathematics. Like in the first edition, the book contains many problems and solutions. E-learning Platform Edition: The paperback version of this book exclusively comes with an e-learning course created by Friedrich Pahlke. This e-learning course has been developed to complement the book and both provide a unique support tool for teaching the subject.